Protein Purification
Active Motif 100 mM PMSF
PMSF can be used to prevent protein degradation from serine proteases during sample preparation.
Cayman Chemical Cdk4 InhIbItr 1mg
A cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by selectively blocking cyclin D1/Cdk4 (IC50 = 0.8 μM); inhibits HCT116 and NCI-H460 tumor cell growth (IC50s 1 cell cycle arrest
Cayman Chemical sPLA2 InhIbItr 5mg
An orally active inhibitor of sPLA2-IIA; protects against intestinal reperfusion injury in rats when given at 10 mg/kg orally; attenuates NF-κB signaling in lung cancer cells and protects against diet-induced metabolic syndrome in rats
Alkali Scientific CellPro™ Trypsin 0.05% protease solution with porcine trypsin, HBSS, EDTA; without calcium, magnesium, 100ml, 10/Case
Trypsin cell detachment solution. Derived from porcine pancreas Gamma irradiated prior to hydration and filling Formulated without calcium and magnesium Portfolio includes various concentrations of Trypsin Protease.
Medchemexpress LLC P38 MAP kinase inhibitor III | 581098-48-8 | MFCD09037547 | 98.8% | 404.50 g/mol | C23H21FN4S | 5 MG
p38 MAP Kinase Inhibitor III is a small-molecule inhibitor of p38 mitogen-activated protein kinase (p38 MAPK) for research use. It shows in vitro activity (IC50 ≈ 0.9 μM) and reduces proinflammatory cytokine release, provided as a solid with high purity and documented solubility and storage conditions for both in vitro and in vivo formulations.
- Inhibits p38 MAP kinase (IC50 ≈ 0.9 μM).
- Reduces IL-1β and TNF-α release (IC50 0.37 μM and 0.044 μM).
- High purity suitable for research applications.
- Good solubility in DMSO and DMF for stock solutions.
- Formulatable for in vivo dosing at ≥ 5 mg/mL in recommended vehicles.
- Stable as a powder at -20°C for long-term storage.
Cayman Chemical SIRT12 InhIbItr IV 5mg
A cell-permeable inhibitor of SIRT1 (IC50 = 56 µM) and SIRT2 (IC50 = 59 µM); less effectively inhibits SIRT5 (IC50 >300 µM) and has no effect on class I and II HDACs; sensitizes H460 lung cancer cells to etoposide and paclitaxel; blocks a SIRT1-dependent hypoxic response in vivo
Apexbio Technology LLC Deacetylase Inhibitor Cocktail (100 in 70% DMSO), 1ml x 50
maintain the acetylation state of proteins Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Cell Counting Kit-8 (CCK-8), 6X5ml (3000 tests)
Our product Cell Counting Kit-8 (CCK-8) provide a more convenient and sensitive method for the research of cell number determination and cell proliferationtotoxicity assay than previous ways. The kit utilizes a highly water-soluble tetrazolium salt, WST-8, which produces a water-soluble formazan dye upon reduction in the presence of an electron mediator. The amount of the formazan generated by dehydrogenases is directly in proportion to the numbers of living cells. The detection sensitivity by CCK-8 is higher than other tetrazolium salts such as MTT, XTT, MTS or WST-1. Other sizes are available. Please inqury us for quote.
Cayman Chemical PKR InhIbItr 5mg
Binds the ATP-binding site of PKR and blocks autophosphorylation (IC50 = 186-210 nM); protects neuroblastoma cells against cell damage triggered by ER stress; prevents phosphorylation of FADD, preventing apoptosis; reduces phosphorylation of PKR and eIF2α in the brain, enhancing long-term memory storage
Cayman Chemical HAT InhIbItr II 5mg
A cell-permeable, selective inhibitor of the HAT p300 (IC50 = 5 µM)
Medchemexpress LLC HY-112136 10mg Medchemexpress, TAO Kinase inhibitor 1 CAS:850467-66-2 Purity:>98%
Medchemexpress, HY-112136 10mg TAO Kinase inhibitor 1 CAS:850467-66-2 TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Protease Inhibitor Cocktail (EDTA-Free, 200X in DMSO), 1ml
Equivalent to Sigma P1860, for use in tissue culture media to prevent proteolytic degradation of secreted proteins. Other sizes are available. Please inqury us for quote.
Selleck Chemical LLC Crenolanib (CP-868596) 5mg 670220-88-9 ARO 002
Crenolanib (CP-868596, ARO 002) is a potent and selective inhibitor of PDGFR?/? with Kd of 2.1 nM/3.2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src. Crenolanib helps to induce mitophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Phenol, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]- | 1638-41-1 | MFCD00397032 | 99.0% | 456.94 g/mol | C12H4Cl6O4S | 5 MG
p38 MAP Kinase Inhibitor IV is an ATP-competitive inhibitor selective for p38α and p38β MAPKs, used as a biochemical tool to probe p38 signaling. It has IC50 values of 0.13 μM (p38α) and 0.55 μM (p38β), and is supplied as a high-purity solid for research applications.
- ATP-competitive inhibitor with defined IC50 values for mechanistic studies.
- High purity (99.0%) for reliable biochemical and cellular assays.
- Solid powder form for convenient storage and handling.
- Recommended storage conditions provided to preserve stability.
- Molecular weight and formula supplied for analytical and formulation work.
Cayman Chemical PRMT4CARM1 InhIbItr 1mg
A selective inhibitor of PRMT4/CARM1 (IC50 = 7.1 µM); reduces the prostate-specific antigen promoter activity in human prostate cancer LNCaP cells